Infertility Clinical Trials at CHR
CHR is committed to fertility research and education. As a leading fertility center focused with rigorous fertility research program, CHR is always conducting multiple fertility studies. Below are three current clinical trials for which we are actively recruiting participants. For a list of fertility research publications that came out as a result of CHR's research activities, please refer to our publications list.
Clinical Trial NCT00650754: DHEA and Premature Ovarian Aging
The experimental focus of this project is on the interaction of DHEA treatment on pregnancy in women with otherwise unexplained infertility and evidence of premature ovarian aging (POA). Participants are randomized into two groups, one receiving dehydroepiandrosterone (DHEA) supplementation and the other receiving placebo.
If you are interested in participating in this DHEA study, please read more about the DHEA study and fill out the application. (These two links will take you to an external site, InfertilityTrials.com, which CHR maintains.
Clinical Trial NCT01202656: Effect of G-CSF on Thin Endometrium
This is a trial designed to test whether granulocyte colony stimulating factor (G-CSF, Neupogen) can increase the rate of embryo implantation following IVF and embryo transfer. Preliminary data at CHR and elsewhere suggest that intrauterine infusion of G-CSF can improve endometrial development and can increase implantation rates of embryos.
Clinical Trial NCT01202643: Effect of G-CSF on Poor Endometrial Development During IVF
The purpose of this study is to investigate the effect of G-CSF on endometrial thickness in women who have failed reaching minimal endometrial thickness by standard treatments, to assess how many reach embryo transfer and what implantation and pregnancy rates are in comparison to control patients. The study will be conducted in women undergoing transfer of previously cryopreserved embryos or undergoing transfer of embryos from donor eggs.
This G-CSF study is recruiting patients by invitation only.
Clinical Trial NCT01662466: Effect of Testosterone Supplementation vs Placebo on Embryo Quality among Women with Diminished Ovarian Reserve Undergoing IVF
The purpose of this study is to determine the effect of treatment with trans-dermal testosterone cream compared to placebo on measures of ovarian reserve, oocyte and embryo quality, and pregnancy rates among women with evidence of diminished ovarian reserve that have persistently low serum testosterone and free testosterone after compelting six previous weeks of DHEA supplementation.
More detailed explanation is avilable on the testosterone ovarian reserve study page.
Last updated: August 15, 2012