Oocyte Control of Ovarian Follicular Development
||John Eppig, PhD|
Professor, The Jackson Laboratory
|Agenda||Cocktails: 6 p.m.|
Presentation: 7 p.m.
Dinner: 8 p.m.
Precise coordination between mammalian precursor egg cell (oocyte) and ovarian follicle development is essential in order to provide an egg that is fully competent to undergo fertilization and embryo development. A system of metabolic cooperation exists, in which oocytes promote the expression of genes in cumulus cells for processes that oocytes cannot carry out efficiently themselves, such as amino acid transport and glucose oxidation. In other words, the oocyte out-sources these processes to the cumulus cells. In turn, the cumulus cells pass the essential products of these processes to the oocyte for use in development. The same system allows the oocytes to regulate the metabolic pathways in the follicle cells to control the rate of follicular development. Oocytes provide the cumulus cells with signals that enable the cumulus cells to respond to preovulatory hormonal stimulus by both undergoing processes essential for ovulation and sending a return signal to the oocyte triggering the resumption of meiosis. The lecture will cover these remarkable mechanisms that coordinate the maturation of both the oocyte and cumulus cells, culminating in the ovulation of an egg ready for fertilization.
Hospoda's location--in the same building as the 100-plus-year-old Bohemian National Hall, an important insitution for Czech and Slovak culture in New York City--is testament to the restaurant's solid Czech roots. In a sleek yet serene setting, Hospoda offers a unique culinary experience that combines the finest Czech pilsner (as well as local beer and well-curated wine list) with seasonal contemporary cuisine with strong suggestions of its Czech heritage. Expertly executed, Hospoda's veal schnitzel is a lighter, fresher update to the traditionally hearty dish. Slow-baked rabbit comes flavored with a rich, bacon-accented reduction of red cabbage, instead of a mound of it on the side.
Please join us at the Hospoda, for an evening of cutting-edge continuing medical education, followed by fun and festivities!
The Center for Human Reproduction (CHR) has, following its charter, for over 20 years been an independent provider of complimentary continuous medical education. CHR takes full responsibility for balance, objectivity and scientific rigor of all information presented. Selection of speakers, topics and content is independent of all outside commercial interests. These events accept reservation on a first-come, first-served basis. Eligibility criteria for free admission: (i) actively practicing physicians in specialty areas relating to reproduction; ii) medical students; iii) scientists in clinical or research area related to reproduction. If you are registering for the first time this academic year, please email a copy of your professional ID with this registration. Space permitting, interested parties who do not qualify for free admission will be offered admission for a donation of $150 at the door to the Foundation of Reproductive Medicine. CHR reserves the right to refuse entry to the event once capacity is reached.
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