Driving Force behind CHR’s Clinical Success
CHR is a rare private fertility center that combines clinical fertility care with a robust clinical and laboratory research program. In over 30 years since its inception, CHR researchers have published hundreds of research papers, many in prestigious medical journals like Journal of the American Medical Association (JAMA) and New England Journal of Medicine (NEJM). CHR’s medical journal publications are listed below.
Some of CHR’s original research findings brought revolutionary new approaches to the field of reproductive endocrinology and infertility. Involvement of autoimmunity in endometriosis is one; the now-routine transvaginal egg retrieval is another; and the most recent example is the introduction of DHEA supplementation into the treatment of women with diminished ovarian reserve.
CHR Explains
CHR’s focus has been the mechanism and treatment of diminished ovarian reserve for over a decade now, and many of our research publications are in this area. In the past few years, CHR has also expanded its laboratory research division significantly with 3 PhD-level scientists to conduct translational research in molecular biology and genetics. CHR’s Medical Director and Chief Scientist, Dr. Norbert Gleicher, emphasizes rigorous translational research because research is what drives innovation in fertility treatment at CHR, and our patients benefit directly from our research findings, which are “translated” into our clinical care program.
Infertility Clinical Trials
Clinical trials are considered the gold standard of research, and at any given time, CHR is likely to have more than one ongoing clinical trials. Some clinical trials recruit participants, while others may be open by invitation only.
Is Embryo Cryopreservation Causing Macrosomia-and What Else?
Citation Page #: 2020; 28;11:19.
Journal: Frontiers in endocrinology
Author Publication: Orvieto R, Kishenbaum M, Gleicher N.
Link: View Publication
Date: 2020
Categories: Default
Transiently increased risk of breast cancer after childbirth: implications for fertility treatments and surrogacy
Citation Page #: 2020; 35(6):1253-1255.
Journal: Human Reproduction
Author Publication: Zeev B, Gleicher N, Adashi EY.
Link: View Publication
Date: 2020
Categories: Default Egg Donation IVF
The PGS/PGT-A controversy in IVF addressed as a formal conflict resolution analysis
Citation Page #: 2020; 37(3):677-687
Journal: Journal of Assisted Reproduction and Genetics
Author Publication: Mochizuki L, Gleicher N.
Link: View Publication
Date: 2020
Categories: Default IVF Research
Not even noninvasive cell-free DNA can rescue preimplantation genetic testing
Citation Page #: 2019;116(44):21976-21977
Journal: Proceedings of the National Academy of Sciences of the United States of America
Author Publication: Gleicher N, Barad DH.
Link: View Publication
Date: 2019
Categories: Testing & Diagnostics
Why is use of donor eggs not viewed as treatment failure? A call for improvements in treatments with autologous oocytes
Citation Page #: 2020; 37(7):1583-1588.
Journal: Journal of Assisted Reproduction and Genetics
Author Publication: Gleicher, N, Barad, DH, Adashi, EY.
Link: View Publication
Date: 2020
Categories: Egg Donation Failed IVF IVF Success Rates IVF
Euploid miscarriage is associated with elevated serum C-reactive protein levels in infertile women: a pilot study
Citation Page #: 2020;301(3):831-836.
Journal: Archives of gynecology and obstetrics
Author Publication: Weghofer A, Barad DH, Darmon SK, Kushnir VA, Albertini DF, Gleicher N.
Link: View Publication
Date: 2020
Categories: Repeated Miscarriages Research
Preimplantation genetic testing for aneuploidy (PGT-A)-finally revealed
Citation Page #: 2020; 37(3):669-672.
Journal: Journal of Assisted Reproduction and Genetics
Author Publication: Orvieto R, Gleicher N.
Link: View Publication
Date: 2020
Categories: IVF Research
Worldwide decline of IVF birth rates and its probable causes.
Citation Page #: 2019(3):hoz017.
Journal: Human Reproduction Open
Author Publication: Gleicher N, Kushnir VA, Barad DH.
Link: View Publication
Date: 2019
Categories: IVF Success Rates Testing & Diagnostics
Not even noninvasive cell-free DNA can rescue preimplantation genetic testing.
Citation Page #: Epub ahead of print
Journal: Proceedings of the National Academy of Sciences
Author Publication: Gleicher N, Barad DH.
Link: View Publication
Date: 2019
Categories: PGD, PGS & PGT-A Testing & Diagnostics
Reduced RNA expression of the FMR1 gene in women with low (CGGn
Citation Page #: 13(12):e0209309.
Journal: PLoS ONE
Author Publication: Wang Q, Barad DH, Darmon SK, Kushnir VA, Wu YG, Lazzaroni-Tealdi E, Zhang L, Albertini DF, Gleicher N.
Link: View Publication
Date: 2018
Categories: Diminished Ovarian Reserve FMR1 Testing & Diagnostics