In Focus: Scratching the surface of ovarian tissue

Posted on Dec 02, 2016

skin55 Scratching the surface. This confocal micrograph provides a glimpse (an unusual one at that) of what the outer portions of the ovary look like if one were to take a just a shallow slice of tissue from the ovarian surface, such as might be done in the case of a biopsy.

From left to right, the image depicts an epithelium (red stipple), which sits on top of a fibrous matrix (green) and beneath which are cells (blue) that represent the ovarian stroma. The latter is where primordial follicles, each containing a potential egg, can reside for many years before being called into action when a follicle is stimulated to grow.

Such tissue preparations are now being studied in many laboratories around the world to understand what the signals are that tell a follicle to remain “asleep” or “wake-up” in anticipation of it undergoing ovulation sometime in the future.

Norbert Gleicher, MD, FACOG, FACS

Norbert Gleicher, MD, FACOG, FACS

Norbert Gleicher, MD, leads CHR’s clinical and research efforts as Medical Director and Chief Scientist. A world-renowned specialist in reproductive endocrinology, Dr. Gleicher has published hundreds of peer-reviewed papers and lectured globally while keeping an active clinical career focused on ovarian aging, immunological issues and other difficult cases of infertility.

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