During the process of egg retrieval, many of the cells that line the ovarian follicle are harvested and used for research. These cells, known as granulosa cells, can be cultured in plastic dishes outside the body where they will continue to divide and eventually become progesterone secreting lutein cells. In this month’s image, we take a close look at the inner workings of a colony granulosa cells that have been labeled with colored dyes to make certain elements of their internal structure apparent. In yellow, the DNA-containing nucleus of each cell can be seen and in pink, the delicate fibers of the cytoskeleton are observed coursing throughout the interior of human granulosa cells.
This is a part of the May 2017 CHR VOICE.