Published in Fertility & Sterility.
OBJECTIVE: To determine whether a relationship exists between vitamin D (25OH-D) levels and ovarian reserve parameters (antimüllerian hormone [AMH] and FSH levels) in a large cohort of infertile women with a high prevalence of diminished ovarian reserve.
DESIGN: Retrospective cohort study.
SETTING: Academically affiliated private fertility center.
PATIENT(S): A total of 457 infertile women 21-50 years of age who had baseline hormone measurements.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Statistical analyses to determine whether a relationship exists between AMH, FSH, and serum 25OH-D levels.
RESULT(S): As defined by 25OH-D
CONCLUSION(S): Vitamin D levels were not associated with ovarian reserve in a large group of infertile women with a high prevalence of diminished ovarian reserve. Previously reported vitamin D-associated outcomes in infertility patients may, therefore, be mediated by factors other than ovarian reserve.
Citation Page #: 110(4):761-766.e1.
Journal: Fertility & Sterility
Author Publication: 424. Shapiro AJ, Darmon SK, Barad DH, Gleicher N, Kushnir VA.
Publication Link: https://linkinghub.elsevier.com/retrieve/pii/S0015-0282(18)30406-0
Date: 2018
Norbert Gleicher, MD, FACOG, FACS
Norbert Gleicher, MD, leads CHR’s clinical and research efforts as Medical Director and Chief Scientist. A world-renowned specialist in reproductive endocrinology, Dr. Gleicher has published hundreds of peer-reviewed papers and lectured globally while keeping an active clinical career focused on ovarian aging, immunological issues and other difficult cases of infertility.