Diminished Ovarian Reserve
Effective treatment of DOR starts with timely diagnosis. Timely diagnosis is crucial because once the ovarian reserveovarian reserve begins declining, it continues to decline with time. The sooner diminished ovarian reserve can be diagnosed, the sooner effective treatment can begin, and the sooner the treatment starts, the better the pregnancy chances are.
"Don't 'wait and see' or postpone treatment for DOR. Ovarian reserve can deteriorate quickly."Dr. Norbert Gleicher
As the center of last resort for women with DOR, CHR meets many women who have postponed treatment for DOR while "waiting for the FSH levels to come down" or while undergoing endless tests at other fertility centers. Unfortunately, without treatment, the chances of pregnancy after 40 can only get worse with time.
The same time-sensitivity applies to women with POA, whose ovarian reserve can deteriorate quickly. Not a day passes when we don't hear patients say, "Doctor, I wish I'd known about your center years ago, when I was doing such and such..."
CHR can diagnose DOR relatively easily with a few blood tests that measure follicle stimulating hormone (FSH)(FSH) and anti-Müllerian hormone (AMH)anti-Müllerian hormone (AMH) levels. High FSH levels and low AMH levels indicate diminished ovarian reserve and the need for aggressive fertility treatment. Of course, especially for younger women who may have POA, it is crucial that their FSH and AMH levels are measured against age-specific baseline values, rather than a universal cut-off values. Following diagnosis, we recommend that patients proceed to treatment as quickly as possible to maximize their pregnancy chances.
Norbert Gleicher, MD, leads CHR’s clinical and research efforts as Medical Director and Chief Scientist. A world-renowned reproductive endocrinologist, Dr. Gleicher has published hundreds of peer-reviewed papers and lectured globally while keeping an active clinical career focused on ovarian aging, immunological issues and other difficult cases of infertility.
Last Updated: October 8, 2018