Pregnancy after 40

Success Rates

CHR's excellent IVF pregnancy rates in women over 40, many of whom had severe diminished ovarian reserve (DOR, or low functional ovarian reserve, LFOR), are among the best in the world. Women over age 40 now constitute more than half of our IVF patients, and we have accumulated enough clinical expertise in this patient population to achieve some remarkable success. Particularly of note for women over 40 trying to get pregnant, in 2015, CHR introduced a new protocol for women over 43 that drastically improved pregnancy rates, where eggs are retrieved earlier than in a typical IVF cycle. We have expanded the use of early retrieval to younger women with premature ovarian aging (POA) with an even larger improvement in IVF outcomes. In 2015, the last year for which clinical pregnancy rates are available, our success rates were as follows:

Patient Age (years) Clinical Pregnancy Rate (%)
40 35.3
41 23.1
42 17.4
43 8.3
≥ 44 5.9

The pregnancy rates above are calculated based on embryo transfer. For our detailed guide on interpreting IVF pregnancy rates at different fertility centers, please refer to our explanation of IVF success rates.

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Last Updated: May 9, 2016

Additional Resources

Commercializing three-parent babies We cannot help but mention an Internet article by Emily Mullin on June 13, 2017, titled “The Fertility Doctor Trying


You must have heard of “Ovarian Rejuvenation” Having a significant presence on the Internet here, CHR receives a large number of inquiries daily about all kinds of

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1/3 of women who have been told they need egg donation actually wind up conceiving at the CHR with their own eggs.