DHEA & Fertility

Typical Dosage

The general dose of DHEA is 75mg daily, which is split into three 25mg doses (to avoid the development of an upset stomach). The treatment is usually started at least 6 weeks prior to the start of IVF cycles, so that DHEA has enough time to affect the ovarian environment for the folliclefollicle that are still small and growing. Supplementation is stopped once a woman has conceived, as the body produces enough DHEA during pregnancy. Because some women take longer than others to convert DHEA into androgensandrogens , the time to get pregnant after DHEA supplementation will be different for each woman.

It is important to note that DHEA alone is unlikely to be effective for women with diminished ovarian reserve who are trying to conceive. To maximize every woman's pregnancy chances, CHR uses DHEA within a well-designed fertility treatment framework. This framework includes ovarian stimulationovarian stimulation protocol tailored to each woman's needs as well as proper management of any contributing infertility factors.

One example of how CHR uses DHEA within a carefully defined fertility treatment framework is testosteronetestosterone monitoring: CHR’s recent research has shown that women whose androgen levels rise while on DHEA supplementation have higher pregnancy rates than those whose androgen levels remain low, even with DHEA. CHR physicians now closely monitor the patients’ androgen (testosterone) levels in order to start their IVF cycles when the androgen levels are within the optimal range.

DHEA should always be taken under the supervision of a physician, as the hormone can interact with some prescription drugs and affect some medical conditions like diabetes, mood disorders, and estrogen-sensitive cancers.

Read more about DHEA Treatment

Last Updated: November 15, 2014

Additional Resources

CHR in the News – Late 2017 Edition During November Vitaly Kushnir, MD, CHR’s Director of Fertility Preservation and Continuous Medical Education, and Associate Scientist, was ...


In Focus: Zona pellucida in ovaries This image shows a small portion of a mouse ovary with many follicles developing, each of which contain a green

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1/3 of women who have been told they need egg donation actually wind up conceiving at the CHR with their own eggs.