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Giving Embryos a Chance: CHR’s Approach to IVF without PGS

The Center for Human Reproduction’s Dr. David H. Barad discusses how CHR gives embryos a “chance to prove themselves” without subjecting them to harm from potentially inaccurate pre-implantation genetic screening (PGS). Avoiding PGS has resulted in higher pregnancy rates and more healthy births at CHR.

What we would rather do at CHR, is not subject these embryos to the potential of damage by biopsy and give them a chance to prove themselves. The kinds of results that appear to be abnormal on the average PGS result are so bizarre that they wouldn’t become babies if they were true. So what you’re betting when you’re doing these transfers is that the result is wrong – that the wrong part of the embryo is biopsied – that the embryo will prove itself when you do the transfer. Our pregnancy rates show that taking this approach and just transferring the embryos, gets us more pregnancies than the other centers would predict (when we get on a per cycle basis).