We noted elsewhere in this newsletter that CHR investigators just published an update [_J Ovarian Res 2018;11(1):2] to their 2015 study in the prestigious medical journal JAMA [2015;314(6):623-624_], which at that time received considerable media attention since it demonstrated that cryopreserved (frozen) donor eggs produced lower pregnancy and live birth rates than fresh donor eggs. Colleagues from the NYU program here in the city strongly criticized our report [Grifo et al, JAMA 2015;314(23):2569-2570], arguing that the difference we had pointed out was only temporary since, as IVF centers gained more experience they would improve. We already then disputed this argument [Kushnir et al., JAMA 2016;314)23)5670], and were proven correct, as the more recent study demonstrated.
Not only did the gap not shrink over ensuing years but it, indeed, grew year by year since then, reaching 10 percentage points two years after the initial study. The writer Jana Visnova, MD, PhD, picked up on this story in an article in the Huffington Post, when quoting CHR’s Vitaly A. Kushnir, MD, in discussing that “egg freezing was not the sure thing some IVF clinics claim.” She, of course, was absolutely correct in making this point when it comes to freezing one’s OWN eggs; but the same also applies to fresh versus frozen donor eggs. FRESH IS ALWAYS BETTER!
This is a part of the March 2018 CHR VOICE.
Norbert Gleicher, MD, leads CHR’s clinical and research efforts as Medical Director and Chief Scientist. A world-renowned specialist in reproductive endocrinology, Dr. Gleicher has published hundreds of peer-reviewed papers and lectured globally while keeping an active clinical career focused on ovarian aging, immunological issues and other difficult cases of infertility.
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