In Focus: Zona pellucida in ovaries

This image shows a small portion of a mouse ovary with many follicles developing, each of which contain a green circle: the zona pellucida. One of our collaborators, Aritro Sen, PhD, at University of Rochester School of Medicine and Dentistry, was recognized recently for the work he has done using the mouse ovary as a model for understanding the role of AMH.

CHR research spans many aspects of female reproductive biology in humans, but as in many of the premier research institutions around the world, animals like the mouse have become an invaluable resource for making discoveries that will eventually aid in the diagnosis and treatment of infertility. One example was the effects of DHEA via androgen receptors in the maturation of oocytes.

This is a part of the June 2017 issue of the VOICE.

Norbert Gleicher, MD, leads CHR’s clinical and research efforts as Medical Director and Chief Scientist. A world-renowned reproductive endocrinologist, Dr. Gleicher has published hundreds of peer-reviewed papers and lectured globally while keeping an active clinical career focused on ovarian aging, immunological issues and other difficult cases of infertility.